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Hybrid AF™ Therapy

Atrial fibrillation is an abnormal heart rhythm caused by erratic electrical signals in the heart. A heart normally creates regular electrical signals that are essential for the heart to beat in a steady, rhythmic way, and pump blood to all parts of the body. Sometimes the electrical signals become irregular, and the heart beats abnormally.

Atrial fibrillation (Afib, AF) is the most commonly diagnosed abnormal heart rhythm (arrhythmia) in the U.S.:

  • 8 million people in the U.S. have Afib1
  • 1.2 million people in the U.S. are diagnosed with Afib each year1
  • 1 in 4 adults will develop Afib in their lifetime2
  • 33 million people around the world have Afib3

What is Hybrid AF Therapy?

Hybrid AF Therapy combines a minimally invasive treatment of the inside and outside of the heart to interrupt the cause of A-fib and restore a normal heart rhythm.

Click here to learn more about Hybrid AF Therapy

Is Hybrid AF Therapy Right for You?

It may be, but only a health care provider can determine the best treatment for you.

With successful Hybrid AF Therapy, there can be other important benefits to the heart, including:

  • Reverse the stretching of the left atrium7
  • Improve heart function overall7
  • Improve your symptoms8
  • Reduce the number of heart medications you need to take7

Talk to your doctor about how to find the right treatment for your stage of atrial fibrillation.


1. Colilla, S. et al. (2013). Estimates of current and future incidence and prevalence of
atrial fibrillation in the U.S. adult population. American journal of cardiology, 112(8), 1142-1147.
2. Lloyd-Jones, D.M., et al. (2004). Lifetime risk for development of atrial fibrillation. Circulation, 110, 1042-1046. doi: 10.1161/01.CIR.0000140263.20897.42
3. Rahman, F., et al. (2014). Global epidemiology of atrial fibrillation. Nature reviews cardiology, 11, 639-654.
7. Benussi, S., & de Maat, G.E. (2018). Atrial remodelling and function: implications for atrial fibrillation surgery. European journal of cardio-thoracic surgery, 53(i1):i2–i8,
8. AtriCure. (2020). PMA P200002 FDA Summary of Safety and Effectiveness Data: Epi-Sense® Guided Coagulation System.

Hybrid AFTherapy is for the treatment of long-standing persistent atrial fibrillation.

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